Spoken Wikipedia Podcast

English Wikipedia articles, read aloud by volunteers

New recordings from Wikimedia Commons publish promptly. Earlier recordings are released in a roughly shuffled order, paced to average about thirty minutes of listening per day. A long recording may therefore be followed by one or more quiet days. Each episode credits its reader and links to the original recording, the article as recorded, and the current article.

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Gene

GAread by Steinsky · recorded April 21, 2005 · 0:17:10 · 11.8 MB

In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce RNA. There are two types of molecular genes: protein-coding genes and non-coding genes. During gene expression (the synthesis of RNA or protein from a gene), DNA is first copied into RNA. RNA can be directly functional or be the intermediate template for the synthesis of a protein. Genes and their regulatory sequences are mainly responsible for determining the physical traits, or the phenotype of an organism. The genotype is the total amount of DNA in an organism including genes, other functional elements, and non-functional DNA. A gene can acquire mutations in its sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a gene, which may be expressed as different phenotypic traits. Populations evolve when the frequencies of alleles shift due mostly to natural selection and genetic drift. Some of these alleles are located in genes.

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